image/svg+xml mt:dom SH2 mt:site Pro mt:dom SH3 P mt:prot Src mt:site Kinase mt:site Tail mt:dom SH2 mt:site Pro mt:dom SH3 mt:prot Src mt:site Kinase mt:site Tail mt:res mt:res P P F P Y416 Y527 Y527 Y416 U U mt:dom SH2 mt:site Pro mt:dom SH3 P mt:prot Src mt:site Kinase mt:site Tail P Y527 Y416 AND Conformation folded mt:dom Dom2 mt:dom Dom1 mt:prot A mt:dom Extracell mt:dom Tnasmem mt:dom Inytracell extracellular intracellular transmembrane R mt:dom Extracell mt:dom Tnasmem mt:dom Inytracell extracellular intracellular transmembrane R mt:pept mt:pept A1 A2 mt:dom Dom2 mt:dom Dom1 mt:prot A mt:pept mt:pept A1 A2 T T F T T (a) (b) (b) (b) (a) (a) (c)