Lenov

Besides my experimental activity on the molecular basis of nicotine addiction, I pursued research in computational biology for more than a decade. Involved in Systems Biology since 1999, my main scientific interest is the study of signal transduction. I participated in several projects on bacterial chemotaxis, and am now focussing on modelling neuronal signalling. My team, at the EMBL-EBI, develops models of signal integration in the dendritic spines of striatal neurons, using continuous or discrete representations, at the population and mesoscopic levels. I participated in the creation of the Systems Biology Markup Language (SBML) and am one of the current editors of SBML. I also play a leading role in several other standardisation efforts within Systems Biology, including SBGN, and the community standard on model quality (MIRIAM). In 2005 I launched BioModels Database, the reference resource for storing and distributing published quantitative models of biological processes.